ORIGINAL ARTICLE
Analyzing research trends and patterns on COVID-19 vaccine hesitancy: A bibliometric study from 2021 to 2022
More details
Hide details
1
College of Medicine and Health Sciences, An-Najah National University, Nablus, PALESTINE
Online publication date: 2023-04-12
Publication date: 2023-07-01
Electron J Gen Med 2023;20(4):em500
KEYWORDS
ABSTRACT
Objective:
To analyze worldwide research trends and patterns on COVID-19 vaccine hesitancy (VH) for the study period from January 2021 to December 2022.
Materials and Methods:
Current descriptive bibliometric study used SciVerse Scopus to retrieve relevant articles.
Results:
The search strategy found 2,886 articles. Scholars from the United States participated in one-third of the retrieved articles. International research collaboration in the field was relatively strong. The retrieved articles focused on healthcare workers, epidemiologic studies, and misinformation. In addition to “Vaccine” and “Vaccines” journals, Lancet and BMJ journals had a leading role in the emergence of the topic. Leading global universities such as Harvard University, Johns Hopkins University, and University College London were most prolific in publishing articles on the topic.
Conclusions:
All countries and regions need information on VH to increase public awareness and counteract antivaccination movements.
REFERENCES (89)
1.
Delany I, Rappuoli R, De Gregorio E. Vaccines for the 21st century. EMBO Mol Med. 2014;6(6):708-20.
https://doi.org/10.1002/emmm.2... PMid:24803000 PMCid:PMC4203350.
4.
Dube E, Laberge C, Guay M, Bramadat P, Roy R, Bettinger J. Vaccine hesitancy: An overview. Hum Vaccin Immunother. 2013;9(8):1763-73.
https://doi.org/10.4161/hv.246... PMid:23584253 PMCid:PMC3906279.
6.
Puri N, Coomes EA, Haghbayan H, Gunaratne K. Social media and vaccine hesitancy: New updates for the era of COVID-19 and globalized infectious diseases. Hum Vaccin Immunother. 2020;16(11):2586-93.
https://doi.org/10.1080/216455... PMid:32693678 PMCid:PMC7733887.
7.
Wawrzuta D, Jaworski M, Gotlib J, Panczyk M. Characteristics of antivaccine messages on social media: Systematic review. J Med Internet Res. 2021;23(6):e24564.
https://doi.org/10.2196/24564 PMid:34085943 PMCid:PMC8214178.
9.
Rao TS, Andrade C. The MMR vaccine and autism: Sensation, refutation, retraction, and fraud. Indian J Psychiatry. 2011;53(2):95-6.
https://doi.org/10.4103/0019-5... PMid:21772639 PMCid:PMC3136032.
10.
Shelby A, Ernst K. Story and science: how providers and parents can utilize storytelling to combat anti-vaccine misinformation. Hum Vaccin Immunother. 2013;9(8):1795-801.
https://doi.org/10.4161/hv.248... PMid:23811786 PMCid:PMC3906284.
11.
Williams SE. What are the factors that contribute to parental vaccine-hesitancy and what can we do about it? Hum Vaccin Immunother. 2014;10(9):2584-96.
https://doi.org/10.4161/hv.285... PMid:25483505 PMCid:PMC4977453.
15.
Lucia VC, Kelekar A, Afonso NM. COVID-19 vaccine hesitancy among medical students. J Public Health (Oxf). 2021;43(3):445-9.
https://doi.org/10.1093/pubmed... PMid:33367857 PMCid:PMC7799040.
16.
Haque A, Pant AB. Efforts at COVID-19 Vaccine development: Challenges and successes. Vaccines (Basel). 2020;8(4):739.
https://doi.org/10.3390/vaccin... Mid:33291245 PMCid:PMC7762169.
18.
Xing K, Tu XY, Liu M, et al. Efficacy and safety of COVID-19 vaccines: A systematic review. Zhongguo Dang Dai Er Ke Za Zhi. 2021;23(3):221-8.
https://doi.org/10.7499/j.issn....
19.
Pormohammad A, Zarei M, Ghorbani S, et al. Efficacy and safety of COVID-19 vaccines: A systematic review and meta-analysis of randomized clinical trials. Vaccines (Basel). 2021;9(5):467.
https://doi.org/10.3390/vaccin... PMid:34066475 PMCid:PMC8148145.
20.
Arora NK, Das MK. COVID-19 vaccine development and the way forward. Indian J Public Health. 2020;64(Supplement): S108-11.
https://doi.org/10.4103/ijph.I... PMid: 32496238.
21.
Mascola JR, Fauci AS. Novel vaccine technologies for the 21st century. Nat Rev Immunol. 2020;20(2):87-8.
https://doi.org/10.1038/s41577... PMid:31712767 PMCid:PMC7222935.
22.
Nossier SA. Vaccine hesitancy: the greatest threat to COVID-19 vaccination programs. J Egypt Public Health Assoc. 2021;96(1):18.
https://doi.org/10.1186/s42506... PMid:34224031 PMCid:PMC8256776.
23.
Lazarus JV, Ratzan SC, Palayew A, et al. A global survey of potential acceptance of a COVID-19 vaccine. Nat Med. 2021; 27(2):225-8.
https://doi.org/10.1038/s41591... PMid:33082575 PMCid:PMC7573523.
24.
Coustasse A, Kimble C, Maxik K. COVID-19 and vaccine hesitancy: A challenge the United States must overcome. J Ambul Care Manage. 2021;44(1):71-5.
https://doi.org/10.1097/JAC.00... PMid:33165121.
25.
Yilmaz S, Colak FU, Yilmaz E, Ak R, Hokenek NM, Altintas MM. Vaccine hesitancy of health-care workers: Another challenge in the fight against COVID-19 in Istanbul. Disaster Med Public Health Prep. 2022;16(3):1134-40.
https://doi.org/10.1017/dmp.20... PMid:34346308 PMCid:PMC8458868.
26.
Amo-Adjei J, Nurzhynska A, Essuman R, Lohiniva AL. Trust and willingness towards COVID-19 vaccine uptake: A mixed-method study in Ghana, 2021. Arch Public Health. 2022;80(1):64.
https://doi.org/10.1186/s13690... PMid:35189963 PMCid:PMC8860287.
27.
Sallam M. COVID-19 vaccine hesitancy worldwide: A concise systematic review of vaccine acceptance rates. Vaccines (Basel). 2021;9(2):160.
https://doi.org/10.3390/vaccin... PMid:33669441 PMCid:PMC7920465.
28.
AlRyalat SAS, Malkawi LW, Momani SM. Comparing bibliometric analysis using PubMed, Scopus, and Web of Science databases. J Vis Exp. 2019;152.
https://doi.org/10.3791/58494 PMid:31710021.
29.
Kokol P, Vošner HB. Discrepancies among Scopus, Web of Science, and PubMed coverage of funding information in medical journal articles. J Med Libr Assoc. 2018;106(1):81-6.
https://doi.org/10.5195/jmla.2... PMid:29339937 PMCid:PMC5764597.
30.
Falagas ME, Pitsouni EI, Malietzis GA, Pappas G. Comparison of PubMed, Scopus, Web of Science, and Google Scholar: Strengths and weaknesses. Faseb J. 2008;22(2):338-42.
https://doi.org/10.1096/fj.07-... PMid:17884971.
31.
van Eck NJ, Waltman L. Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics. 2010;84(2):523-38.
https://doi.org/10.1007/s11192... PMid:20585380 PMCid:PMC2883932.
32.
Wang NX, Liang HG, Jia Y, Ge SL, Xue YJ, Wang ZN. Cloud computing research in the IS discipline: A citation/co-citation analysis. Decis Support Syst. 2016;86(C):35-47.
https://doi.org/10.1016/j.dss.....
33.
Cobo MJ, Lopez-Herrera AG, Herrera-Viedma E, Herrera F. Science mapping software tools: Review, analysis, and cooperative study among tools. J Am Soc Inform Sci Technol. 2011;62(7):1382-402.
https://doi.org/10.1002/asi.21....
35.
Sallam M, Al-Sanafi M, Sallam M. A global map of COVID-19 vaccine acceptance rates per country: An updated concise narrative review. J Multidiscip Healthc. 2022;15:21-45.
https://doi.org/10.2147/JMDH.S... PMid:35046661 PMCid:PMC8760993.
36.
Murphy J, Vallieres F, Bentall RP, et al. Psychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom. Nat Commun. 2021;12(1):29.
https://doi.org/10.1038/s41467... PMid:33397962 PMCid:PMC7782692.
37.
Khubchandani J, Sharma S, Price JH, Wiblishauser MJ, Sharma M, Webb FJ. COVID-19 vaccination hesitancy in the United States: A rapid national assessment. J Community Health. 2021;46(2):270-7.
https://doi.org/10.1007/s10900... PMid:33389421 PMCid:PMC7778842.
38.
Lin C, Tu P, Beitsch LM. Confidence and receptivity for COVID-19 vaccines: A rapid systematic review. Vaccines (Basel). 2020;9(1):16.
https://doi.org/10.3390/vaccin... PMid:33396832 PMCid:PMC7823859.
39.
Loomba S, de Figueiredo A, Piatek SJ, de Graaf K, Larson HJ. Measuring the impact of COVID-19 vaccine misinformation on vaccination intent in the UK and USA. Nat Hum Behav. 2021;5(3):337-48.
https://doi.org/10.1038/s41562... PMid:33547453.
40.
Paul E, Steptoe A, Fancourt D. Attitudes towards vaccines and intention to vaccinate against COVID-19: Implications for public health communications. Lancet Reg Health Eur. 2021;1:100012.
https://doi.org/10.1016/j.lane... PMid:33954296 PMCid:PMC7834475.
41.
Schwarzinger M, Watson V, Arwidson P, Alla F, Luchini S. COVID-19 vaccine hesitancy in a representative working-age population in France: A survey experiment based on vaccine characteristics. Lancet Public Health. 2021;6(4): e210-21.
https://doi.org/10.1016/s2468-... PMid:33556325.
42.
Solís Arce JS, Warren SS, Meriggi NF, et al. COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries. Nat Med. 2021;27(8):1385-94.
https://doi.org/10.1038/s41591... PMid:34272499 PMCid:PMC8363502.
44.
Whitehead HS, French CE, Caldwell DM, Letley L, Mounier-Jack S. A systematic review of communication interventions for countering vaccine misinformation. Vaccine. 2023;41(5):1018-34.
https://doi.org/10.1016/j.vacc... PMid:36628653 PMCid:PMC9829031.
45.
Batteux E, Mills F, Jones LF, Symons C, Weston D. The effectiveness of interventions for increasing COVID-19 vaccine uptake: A systematic review. Vaccines (Basel). 2022;10(3):386.
https://doi.org/10.3390/vaccin... PMid:35335020 PMCid:PMC8949230.
47.
Harrison EA, Wu JW. Vaccine confidence in the time of COVID-19. Eur J Epidemiol. 2020;35(4):325-30.
https://doi.org/10.1007/s10654... PMid:32318915 PMCid:PMC7174145.
48.
Dube E, Vivion M, MacDonald NE. Vaccine hesitancy, vaccine refusal and the anti-vaccine movement: Influence, impact and implications. Expert Rev Vaccines. 2015;14(1):99-117.
https://doi.org/10.1586/147605... PMid:25373435.
49.
Dube E, Ward JK, Verger P, MacDonald NE. Vaccine hesitancy, acceptance, and anti-vaccination: Trends and future prospects for public health. Annu Rev Public Health. 2021;42:175-91.
https://doi.org/10.1146/annure... PMid:33798403.
50.
Nazli SB, Yigman F, Sevindik M, Deniz Ozturan D. Psychological factors affecting COVID-19 vaccine hesitancy. Ir J Med Sci. 2022;191(1):71-80.
https://doi.org/10.1007/s11845... PMid:33990893 PMCid:PMC8121491.
51.
Li PC, Theis SR, Kelly D, et al. Impact of an education intervention on COVID-19 vaccine hesitancy in a military base population. Mil Med. 2022;187(11-12):e1449-55.
https://doi.org/10.1093/milmed... PMid:34557913 PMCid:PMC8500140.
52.
Arede M, Bravo-Araya M, Bouchard É, et al. Combating vaccine hesitancy: Teaching the next generation to navigate through the post truth era. Front Public Health. 2018;6:381.
https://doi.org/10.3389/fpubh.... PMid:30693276 PMCid:PMC6339919.
53.
Sweileh WM. Bibliometric analysis of peer-reviewed literature on climate change and human health with an emphasis on infectious diseases. Global Health. 2020;16(1):44.
https://doi.org/10.1186/s12992... PMid:32384901 PMCid:PMC7206222.
54.
Sweileh WM. Bibliometric analysis of peer-reviewed literature on antimicrobial stewardship from 1990 to 2019. Global Health. 2021;17(1):1.
https://doi.org/10.1186/s12992... PMid:33397377 PMCid:PMC7780390.
55.
Sweileh WM. Patient satisfaction with nursing care: A bibliometric and visualization analysis (1950-2021). Int J Nurs Pract. 2022;28(5):e13076.
https://doi.org/10.1111/ijn.13... PMid:35822232.
57.
Hviid A, Hansen JV, Frisch M, Melbye M. Measles, mumps, rubella vaccination and autism: A nationwide cohort study. Ann Intern Med. 2019;170(8):513-20.
https://doi.org/10.7326/M18-21... PMid:30831578.
58.
Plotkin S, Gerber JS, Offit PA. Vaccines and autism: A tale of shifting hypotheses. Clin Infect Dis. 2009;48(4):456-61.
https://doi.org/10.1086/596476 PMid:19128068 PMCid:PMC2908388.
59.
Boulton ML, Carlson BF, Power LE, Wagner AL. Socioeconomic factors associated with full childhood vaccination in Bangladesh, 2014. Int J Infect Dis. 2018;69:35-40.
https://doi.org/10.1016/j.ijid... PMid:29421667.
60.
Qunaibi EA, Helmy M, Basheti I, Sultan I. A high rate of COVID-19 vaccine hesitancy in a large-scale survey on Arabs. Elife. 2021;10.
https://doi.org/10.7554/eLife.... PMid:34042047 PMCid:PMC8205489.
61.
Uddin A, Singh VK. Measuring research output and collaboration in South Asian countries. Curr Sci. 2014;107(1):31-8.
63.
Khan A, Alsofayan Y, Alahmari A, et al. COVID-19 in Saudi Arabia: The national health response. East Mediterr Health J. 2021;27(11):1114-24.
https://doi.org/10.26719/emhj.... PMid:34927716.
64.
Salam AA, Al-Khraif RM, Elsegaey I. COVID-19 in Saudi Arabia: An overview. Front Public Health. 2021;9:736942.
https://doi.org/10.3389/fpubh.... PMid:35186861 PMCid:PMC8847272.
65.
Al Awaidy ST, Khamis F, Al Attar F, et al. COVID-19 in the Gulf Cooperation Council member states: An evidence of effective response. Oman Med J. 2021;36(5):e300.
https://doi.org/10.5001/omj.20... PMid:34552762 PMCid:PMC8441050.
67.
Zhan M, Qin Y, Xue X, Zhu S. Death from COVID-19 of 23 health care workers in China. N Engl J Med. 2020;382(23):2267-8.
https://doi.org/10.1056/NEJMc2... PMid:32294342 PMCid:PMC7179960.
68.
Artiga S, Rae M, Claxton G, Garfield R. Key characteristics of health care workers and implications for COVID-19 vaccination. Kaiser Family Foundation; 2021. Available at:
https://www.kff.org/coronaviru... (Accessed: 8 March 2023).
69.
Kwok KO, Li KK, Lee SS, et al. Multi-centre study on cultural dimensions and perceived attitudes of nurses towards influenza vaccination uptake. J Hosp Infect. 2019; 102(3):337-42.
https://doi.org/10.1016/j.jhin... PMid:30500386.
70.
Lucia VC, Kelekar A, Afonso NM. COVID-19 vaccine hesitancy among medical students. J Public Health. 2021;43(3):445-9.
https://doi.org/10.1093/pubmed... PMid:33367857 PMCid:PMC7799040.
71.
Lockyer B, Islam S, Rahman A, et al. Understanding COVID-19 misinformation and vaccine hesitancy in context: Findings from a qualitative study involving citizens in Bradford, UK. Health Expect. 2021;24(4):1158-67.
https://doi.org/10.1111/hex.13... PMid:33942948 PMCid:PMC8239544.
72.
Hernandez RG, Hagen L, Walker K, O’Leary H, Lengacher C. The COVID-19 vaccine social media infodemic: healthcare providers’ missed dose in addressing misinformation and vaccine hesitancy. Hum Vaccin Immunother. 2021;17(9):2962-4.
https://doi.org/10.1080/216455... PMid:33890838 PMCid:PMC8381841.
73.
Kricorian K, Civen R, Equils O. COVID-19 vaccine hesitancy: misinformation and perceptions of vaccine safety. Hum Vaccin Immunother. 2022;18(1):1950504.
https://doi.org/10.1080/216455... PMid:34325612 PMCid:PMC8920251.
74.
Cuan-Baltazar JY, Muñoz-Perez MJ, Robledo-Vega C, Pérez-Zepeda MF, Soto-Vega E. Misinformation of COVID-19 on the Internet: Infodemiology study. JMIR Public Health Surveill. 2020;6(2):e18444.
https://doi.org/10.2196/18444 PMid:32250960 PMCid:PMC7147328.
75.
Ginossar T, Cruickshank IJ, Zheleva E, Sulskis J, Berger-Wolf T. Cross-platform spread: Vaccine-related content, sources, and conspiracy theories in YouTube videos shared in early Twitter COVID-19 conversations. Hum Vaccin Immunother. 2022;18(1):1-13.
https://doi.org/10.1080/216455... PMid:35061560 PMCid:PMC8920146.
76.
Scannell D, Desens L, Guadagno M, et al. COVID-19 vaccine discourse on Twitter: A content analysis of persuasion techniques, sentiment and mis/disinformation. J Health Commun. 2021;26(7):443-59.
https://doi.org/10.1080/108107... PMid:34346288.
77.
Sweileh WM. Bibliometric analysis of global scientific literature on vaccine hesitancy in peer-reviewed journals (1990-2019). BMC Public Health. 2020;20(1):1252.
https://doi.org/10.1186/s12889... PMid:32807154 PMCid:PMC7433157.
78.
Abid M, Gheraia Z, Abdelli H, Sekrafi H, Diaw A. COVID-19 pandemic and economic impacts in Arab countries: Challenges and policies. Res Glob. 2022;5:100103.
https://doi.org/10.1016/j.resg... PMCid:PMC9595411.
79.
Jain J, Saurabh S, Kumar P, et al. COVID-19 vaccine hesitancy among medical students in India. Epidemiol Infect. 2021;149:e132.
https://doi.org/10.1017/s09502... PMid:34011421 PMCid:PMC8185413.
80.
Kelekar AK, Lucia VC, Afonso NM, Mascarenhas AK. COVID-19 vaccine acceptance and hesitancy among dental and medical students. J Am Dent Assoc. 2021;152(8):596-603.
https://doi.org/10.1016/j.adaj... PMid:34030867 PMCid:PMC7997309.
81.
Venkatesan K, Menon S, Haroon NN. COVID-19 vaccine hesitancy among medical students: A systematic review. J Educ Health Promot. 2022;11:218.
https://doi.org/10.4103/jehp.j... PMid:36177403 PMCid:PMC9514279.
82.
Saied SM, Saied EM, Kabbash IA, Abdo SAE. Vaccine hesitancy: Beliefs and barriers associated with COVID-19 vaccination among Egyptian medical students. J Med Virol. 2021;3(7):4280-91.
https://doi.org/10.1002/jmv.26... PMid:33644891 PMCid:PMC8013865.
83.
Razai MS, Osama T, McKechnie DGJ, Majeed A. COVID-19 vaccine hesitancy among ethnic minority groups. BMJ. 2021;372:n513.
https://doi.org/10.1136/bmj.n5... PMid:33637577.
84.
Bogart LM, Ojikutu BO, Tyagi K, et al. COVID-19 related medical mistrust, health impacts, and potential vaccine hesitancy among Black Americans living with HIV. J Acquir Immune Defic Syndr. 2021;86(2):200-7.
https://doi.org/10.1097/qai.00... PMid:33196555 PMCid:PMC7808278.
85.
Mohan S, Reagu S, Lindow S, Alabdulla M. COVID-19 vaccine hesitancy in perinatal women: A cross sectional survey. J Perinat Med. 2021;49(6):678-85.
https://doi.org/10.1515/jpm-20... PMid:33905622.
87.
Choudrie J, Banerjee S, Kotecha K, Walambe R, Karende H, Ameta J. Machine learning techniques and older adults processing of online information and misinformation: A covid 19 study. Comput Human Behav. 2021;119:106716.
https://doi.org/10.1016/j.chb.... PMid:34866770 PMCid:PMC8631531.
88.
Yeung AWK, Tosevska A, Klager E, et al. Medical and health-related misinformation on social media: Bibliometric study of the scientific literature. J Med Internet Res. 2022;24(1): e28152.
https://doi.org/10.2196/28152 PMid:34951864 PMCid:PMC8793917.
89.
Kwok KO, Li KK, Wei WI, Tang A, Wong SYS, Lee SS. Editor’s choice: Influenza vaccine uptake, COVID-19 vaccination intention and vaccine hesitancy among nurses: A survey. Int J Nurs Stud. 2021;114:103854.
https://doi.org/10.1016/j.ijnu... PMid:33326864 PMCid:PMC7831770.