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ORIGINAL ARTICLE
Confirmed SARS-CoV-2 infection and mortality: Associated factors in hospitalized people 75 and older
1
Geriatrics Unit, Hospital Universitario San Ignacio, Bogotá D.C., COLOMBIA
2
Institute of Aging, School of Medicine, Pontificia Universidad Javeriana, Bogotá D.C., COLOMBIA
3
Geriatrics Service, Clínica del Country, Bogotá D.C., COLOMBIA
4
Department of Internal Medicine and Geriatrics, Hospital Cardiovascular de Cundinamarca, San Mateo, Soacha, COLOMBIA
Online publication date: 2023-03-07
Publication date: 2023-05-01
Electron J Gen Med 2023;20(3):em479
KEYWORDS
ABSTRACT
Introduction:
COVID-19 infection in the elderly posed challenges in health systems and clinical care by health personnel.
Objective:
To describe the factors associated with mortality in persons aged 75 and older with COVID-19 in a high complexity hospital in Bogotá, Colombia.
Methods:
Observational, analytical and retrospective study, including 509 patients aged 75 and older hospitalized with COVID-19.
Results:
40.47% died during hospital stay. It was found that a shorter time of symptom onset at admission, a respiratory rate greater than 20 breaths per minute, having thrombocytopenia, elevated lactate dehydrogenase and elevated D-dimer were associated with higher in-hospital mortality.
Conclusions:
There is an association between mortality and the presence of dyspnea, fever and delirium. Paraclinical results with lactate dehydrogenase >350 (U/L), the presence of elevated D-dimer greater than 1,000 μg/L, as well as a Pa02/Fi02 ratio with a median of less than 90, were associated with higher mortality.
COVID-19 infection in the elderly posed challenges in health systems and clinical care by health personnel.
Objective:
To describe the factors associated with mortality in persons aged 75 and older with COVID-19 in a high complexity hospital in Bogotá, Colombia.
Methods:
Observational, analytical and retrospective study, including 509 patients aged 75 and older hospitalized with COVID-19.
Results:
40.47% died during hospital stay. It was found that a shorter time of symptom onset at admission, a respiratory rate greater than 20 breaths per minute, having thrombocytopenia, elevated lactate dehydrogenase and elevated D-dimer were associated with higher in-hospital mortality.
Conclusions:
There is an association between mortality and the presence of dyspnea, fever and delirium. Paraclinical results with lactate dehydrogenase >350 (U/L), the presence of elevated D-dimer greater than 1,000 μg/L, as well as a Pa02/Fi02 ratio with a median of less than 90, were associated with higher mortality.
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