Aim: Polycystic ovary syndrome (PCOS), one of the commonest endocrinopathies in the human, is known to be associated with risk factors for cerebrovascular disease. The aim of this study was to determine whether there was a change in cerebral blood flow volume in PCOS. Methods: We reported 30 women with PCOS and 20 healthy women as control group. We detected internal carotid (ICA), vertebral artery (VA) and cerebral blood flow (CBF) volumes using color duplex sonography. Results: There were no significant differences between patients with PCOS and control group in CBF volumes or the bilateral sum of flow volumes in the ICA and VA. There was also no statistically significant correlation between sum of bilateral VA, ICA and CBFV with age in both groups. However bilateral mean velocity of VA was significantly lower in patients with PCOS compared to control group. Conclusion: It seems that although endocrine and metabolic abnormalities occur in patients with PCOS there are no abnormality of CBF volume in young patients. However, a further study with a wider age range is required.