ORIGINAL ARTICLE
Factors Affecting Survival in Small Cell Lung Cancer
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1
Okmeydanı Training and Research Hospital, Medical Oncology Clinic, Istanbul
2
Kanuni Sultan Süleyman Training and Research Hospital, Chest Diseases Clinic, Istanbul
3
Süleyman Demirel University, Medical Oncology Clinic, Isparta
4
Süleyman Demirel University, Department of Biometrics and Genetics, Isparta
5
Haseki Training and Research Hospital, Clinic of Internal Medicine, Istanbul
Publication date: 2016-08-06
Corresponding author
Abdullah Sakin
Okmeydanı Eğitim ve Araştırma Hastanesi,
Tıbbi Onkoloji Kliniği, İstanbul
Eur J Gen Med 2016;13(3):37-41
KEYWORDS
ABSTRACT
Background:
Small cell lung cancer (SCLC) constitutes about 15-25 % of lung cancers with high mortality rate. Herein we observed the effect of parameters at the time
of diagnosis to survival of cases with SCLC.
Methods:
We evaluated 65 patients who were followed up in our oncology department retrospectively.
Results:
Tumor location and stage at the time of diagnosis, smoking history, accompanying comorbidities, ECOG PS, laboratory parameters and treatments applied in
pursuit were evaluated. 3-month survival rate of patients was 75.9%, 50.2% for 6-month, 21.4% for 1 year, and 5.5% for 2 years during follow up. ECOG PS and stage
were found statistically significant risk factors in model created to determine overall survival.
Conclusion:
Performance score at the time of diagnosis, stage and presence of liver metastasis are identified as prognostic factors for SCLC and of these factors are
quite valuable to predict the clinical outcome.