Depilation through laser hair removal has gained popularity due to its long-lasting effects, which can last for several months and, in some cases, be considered permanent. This method also improves quality of life. However, common complications include blistering, pigmentary changes, and scabbing. Folliculitis is rare, with most cases being mild and transient. We hereby report on a 33-year-old healthy Thai male who rapidly developed severe folliculitis one day after undergoing diode laser treatment, which combined three wavelengths (755 nm, 810 nm, and 1,064 nm) into a single pulse. The condition improved significantly following a short course of prednisolone and topical benzoyl peroxide. At the 4-week follow-up, the lesions had nearly resolved, with only a few erythematous papules and hyperpigmented follicular macules remaining and no scarring. Further studies are needed to clarify the mechanism of folliculitis after hair removal laser treatment, enabling more effective prevention and management for patients.