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ORIGINAL ARTICLE
Post-traumatic stress disorder burden among female Syrian war refugees is associated with dysmenorrhea severity but not with the analgesics
1
Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Yarmouk University, Irbid, JORDAN
2
Division of Psychology, Faculty of Natural Sciences, University of Stirling, Stirling, SCOTLAND
3
Prince Hamza Hospital, Amman, JORDAN
Online publication date: 2023-03-16
Publication date: 2023-07-01
Electron J Gen Med 2023;20(4):em485
KEYWORDS
ABSTRACT
Dysmenorrhea association with post-traumatic stress disorder (PTSD) has not been studied in refugees. We aimed to examine the associations between dysmenorrhea severity, dysmenorrhea analgesics self-medications, and PTSD in a cohort of Syrian war refugees residing in Jordan.
This is a cross-sectional study based on predetermined inclusion criteria held at Caritas primary care centers in Jordanian districts between September and October 2022. The participants’ demographics and analgesic self-medication type were recorded through a structured questionnaire. The dysmenorrhea severity was measured by (working ability, location, intensity, days of pain, and dysmenorrhea) WaLiDD scale, PTSD was measured by Davidson trauma scale (DTS)-DSM-IV.
Data from 347 Syrian female war refugees were analyzed. The multivariate analysis showed that dysmenorrhea severity demonstrated significantly higher estimates for PTSD (10.48 [6.72-14.23], p=0.001), however, the analgesic type was not associated with PTSD burden.
In conclusion, dysmenorrhea severity, but not self-medication, was associated with a higher PTSD burden.
REFERENCES (42)
1.
American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5-TR). Washington, DC: American Psychiatric Association; 2013. https://doi.org/10.1176/appi.b....
2.
Qureshi SU, Pyne JM, Magruder KM, Schulz PE, Kunik ME. The link between post-traumatic stress disorder and physical comorbidities: A systematic review. Psychiatr Q. 2009;80(2):87-97. https://doi.org/10.1007/s11126... PMid:19291401.
3.
Gilpin NW, Weiner JL. Neurobiology of comorbid post-traumatic stress disorder and alcohol-use disorder. Genes Brain Behav. 2017;16(1):15-43. https://doi.org/10.1111/gbb.12... PMid:27749004 PMCid:PMC5477640.
4.
Yaribeygi H, Panahi Y, Sahraei H, Johnston TP, Sahebkar A. The impact of stress on body function: A review. EXCLI J. 2017;16:1057-72.
5.
Shin G, Lee SJ. Mental health and PTSD in female North Korean refugees. Health Care Women Int. 2015;36(4):409-23. https://doi.org/10.1080/073993... PMid:24020655.
6.
Kim E, Yun M, Jun JY, Park W-S. Pre-migration trauma, repatriation experiences, and PTSD among North Korean refugees. J Immigr Minor Health. 2019;21(3):466-72. https://doi.org/10.1007/s10903... PMid:29651589.
7.
Al-Smadi AM, Tawalbeh LI, Gammoh OS, Ashour AF, Shajrawi A, Attarian H. Relationship between anxiety, post-traumatic stress, insomnia and fibromyalgia among female refugees in jordan: A cross-sectional study. J Psychiatr Ment Health Nurs. 2021;28(4):738-47. https://doi.org/10.1111/jpm.12... PMid:33448096.
8.
Gammouh OS, Al-Smadi AM, Tawalbeh LI, Khoury LS. Chronic diseases, lack of medications, and depression among Syrian refugees in Jordan, 2013-2014. Prev Chronic Dis. 2015;12:E10. https://doi.org/10.5888/pcd12.... PMid:25633485 PMCid:PMC4310712.
9.
Regehr C, Carey M, Wagner S, et al. Prevalence of PTSD, depression and anxiety disorders in correctional officers: A systematic review. Corrections. 2021;6(3):229-41. https://doi.org/10.1080/237746....
10.
Jamil H, Nassar-McMillan SC, Salman WA, Tahar M, Jamil L. Iraqi Gulf War veteran refugees in the U.S.: PTSD and physical symptoms. Soc Work Health Care. 2006;43(4):85-98. https://doi.org/10.1300/J010v4... PMid:16966311.
11.
Arcel LT, Popovic S, Kucukalic A, Bravo-Mehmedbasic A. Treatment of torture and trauma survivors in a post-war society. Sarajevo: Association for Rehabilitation of Torture Victims–Center for Torture Victims; 2003.
12.
Olff M. Sex and gender differences in post-traumatic stress disorder: An update. Eur J Psychotraumatol. 2017;8(sup4):1351204. https://doi.org/10.1080/200081... PMCid:PMC5632782.
13.
Takeda T, Tadakawa M, Koga S, Nagase S, Yaegashi N. Relationship between dysmenorrhea and posttraumatic stress disorder in Japanese high school students 9 months after the Great East Japan Earthquake. J Pediatr Adolesc Gynecol. 2013;26(6):355-7. https://doi.org/10.1016/j.jpag... PMid:24075088.
14.
Tolin DF, Foa EB. Sex differences in trauma and posttraumatic stress disorder: A quantitative review of 25 years of research. Psychol Bull. 2008;132(6):959-92. https://doi.org/10.1037/0033-2... PMid:17073529.
15.
Breslau N. Gender differences in trauma and posttraumatic stress disorder. J Gend Specif Med. 2002;5(1):34-40.
16.
Christiansen DM, Hansen M. Accounting for sex differences in PTSD: A multi-variable mediation model. Eur J Psychotraumatol. 2015;6:26068. https://doi.org/10.3402/ejpt.v... PMid:25604705 PMCid:PMC4300366.
17.
Murthy RS, Lakshminarayana R. Mental health consequences of war: A brief review of research findings. World Psychiatry. 2006;5(1):25-30.
18.
Arcel LT, Kastrup MC. War, women and health. NORA-Nordic J Fem Gend Res. 2004;12(1):40-7. https://doi.org/10.1080/080387....
19.
Kizilhan JI. Trauma and pain in family-orientated societies. Int J Environ Res Public Health. 2018;15(1):44. https://doi.org/10.3390/ijerph... PMid:29283370 PMCid:PMC5800143.
20.
Karstoft K-I, Armour C, Elklit A, Solomon Z. The role of locus of control and coping style in predicting longitudinal PTSD-trajectories after combat exposure. J Anxiety Disord. 2015;32:89-94. https://doi.org/10.1016/j.janx... PMid:25890288.
21.
Gammoh OS, Al-Smadi A, Tayfur M, et al. Syrian female war refugees: Preliminary fibromyalgia and insomnia screening and treatment trends. Int J Psychiatry Clin Pract. 2020;24(4):387-91. https://doi.org/10.1080/136515... PMid:32657625.
22.
Rometsch C, Denkinger JK, Engelhardt M, et al. Pain, somatic complaints, and subjective concepts of illness in traumatized female refugees who experienced extreme violence by the “Islamic State”(IS). J Psychosom Res. 2020;130:109931. https://doi.org/10.1016/j.jpsy... PMid:31981895.
23.
El Sount CR-O, Windthorst P, Denkinger J, et al. Chronic pain in refugees with posttraumatic stress disorder (PTSD): A systematic review on patients’ characteristics and specific interventions. J Psychosom Res. 2019;118:83-97. https://doi.org/10.1016/j.jpsy... PMid:30078503.
24.
Cohen BE, Maguen S, Bertenthal D, Shi Y, Jacoby V, Seal KH. Reproductive and other health outcomes in Iraq and Afghanistan women veterans using VA health care: Association with mental health diagnoses. Women’s Heal Issues. 2012;22(5):e461-71. https://doi.org/10.1016/j.whi.... PMid:22944901 PMCid:PMC4631402.
25.
Bajalan Z, Moafi F, MoradiBaglooei M, Alimoradi Z. Mental health and primary dysmenorrhea: A systematic review. J Psychosom Obstet Gynecol. 2019;40(3):185-94. https://doi.org/10.1080/016748... PMid:29745745.
26.
Szarka A, Rigo JJ, Lazar L, Beko G, Molvarec A. Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array. BMC Immunol. 2010;11:59. https://doi.org/10.1186/1471-2... PMid:21126355 PMCid:PMC3014878.
27.
Wu M-H, Lu C-W, Chuang P-C, Tsai S-J. Prostaglandin E2: The master of endometriosis? Exp Biol Med (Maywood). 2010;235(6):668-77. https://doi.org/10.1258/ebm.20... PMid:20511671.
28.
WHO. Guidelines for the regulatory assessment of medicinal products for use in self-medication. World Health Organization; 2000. Available at: https://apps.who.int/iris/hand... (Accessed: 6 February 2023).
29.
Armour M, Parry K, Al-Dabbas MA, et al. Self-care strategies and sources of knowledge on menstruation in 12,526 young women with dysmenorrhea: A systematic review and meta-analysis. PLoS One. 2019;14(7):e0220103. https://doi.org/10.1371/journa... PMid:31339951 PMCid:PMC6655766.
30.
De Sanctis V, Soliman AT, Daar S, et al. Prevalence, attitude and practice of self-medication among adolescents and the paradigm of dysmenorrhea self-care management in different countries. Acta Biomed. 2020;91(1):182-92.
31.
Hawkey AJ, Ussher JM, Perz J, Metusela C. Experiences and constructions of menarche and menstruation among migrant and refugee women. Qual Health Res. 2017;27(10):1473-90. https://doi.org/10.1177/104973... PMid:27742765.
32.
Teherán AA, Piñeros LG, Pulido F, Mejía Guatibonza MC. WaLIDD score, a new tool to diagnose dysmenorrhea and predict medical leave in University students. Int J Womens Health. 2018;10:35-45. https://doi.org/10.2147/IJWH.S... PMid:29398923 PMCid:PMC5775738.
33.
Davidson JRT, Book SW, Colket JT, et al. Assessment of a new self-rating scale for post-traumatic stress disorder. Psychol Med. 1997;27(1):153-60. https://doi.org/10.1017/S00332... PMid:9122295.
34.
Ali M, Farooq N, Bhatti MA, Kuroiwa C. Assessment of prevalence and determinants of posttraumatic stress disorder in survivors of earthquake in Pakistan using Davidson trauma scale. J Affect Disord. 2012;136(3):238-43. https://doi.org/10.1016/j.jad.... PMid:22209270.
35.
Kohler O, Krogh J, Mors O, Benros ME. Inflammation in depression and the potential for anti-inflammatory treatment. Curr Neuropharmacol. 2016;14(7):732-42. https://doi.org/10.2174/157015... PMid:27640518 PMCid:PMC5050394.
36.
Lehrer S, Rheinstein PH. Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce suicidal ideation and depression. Discov Med. 2019;28(154):205-12.
37.
Hinz B, Brune K. Paracetamol and cyclooxygenase inhibition: Is there a cause for concern? Ann Rheum Dis. 2012;71(1):20-5. https://doi.org/10.1136/ard.20... PMid:22039164.
38.
Taler M, Gil-Ad I, Lomnitski L, et al. Immunomodulatory effect of selective serotonin reuptake inhibitors (SSRIs) on human T lymphocyte function and gene expression. Eur Neuropsychopharmacol. 2007;17(12):774-80. https://doi.org/10.1016/j.euro... PMid:17499975.
39.
Knights KM, Mangoni AA, Miners JO. Defining the COX inhibitor selectivity of NSAIDs: implications for understanding toxicity. Expert Rev Clin Pharmacol. 2010;3(6):769-76. https://doi.org/10.1586/ecp.10... PMid:22111779.
40.
Müller N, Schwarz MJ, Dehning S, et al. The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: Results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine. Mol Psychiatry. 2006;11(7):680-4. https://doi.org/10.1038/sj.mp.... PMid:16491133.
41.
Al-Smadi AM, Halaseh HJ, Gammoh OS, Ashour AF, Gharaibeh B, Khoury LS. Do chronic diseases and availability of medications predict post-traumatic stress disorder (PTSD) among Syrian refugees in Jordan? Pak J Nutr. 2016;15(10):936-41. https://doi.org/10.3923/pjn.20....
42.
von Känel R, Hepp U, Kraemer B, et al. Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder. J Psychiatr Res. 2007;41(9):744-52. https://doi.org/10.1016/j.jpsy... PMid:16901505.
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