The association between sarcoidosis and AIHA is extremely rare. Herein, we report a novel case of this association in which will focus on the pathogenesis and the prognosis. Mr. A. F., a 43 year old patient was presented to internal medicine department in November 2007 with bilateral inguinal adenopathies. The diagnosis of sarcoidois was made on the basis of identification of granulomas in salivary biopsy with the negativity of other etiological investigations. He was treated with steroids with favorable outcome. Seven years later, he was presented with deep autoimmune hemolytic anemia which was not related to sarcoidoisis. He was again put on steroids with favorable evolution.
REFERENCES(17)
1.
Chernow K, Donegan T, Milman T, Henry D. Sarcoidosis, complete heart block, and warm autoimmune hemolytic anemia in a young woman. J Community Support Oncol., 2015 Apr;13(4):159-61. https://doi.org/10.12788/jcso.... PMid:26102609.
Davis AE, Belber JP, Movitt ER. The association of hemolytic anemia with sarcoidosis. Blood, 1954 Apr;9(4):379-83. https://doi.org/10.1182/blood.... PMid:13149623.
Yasuda N, Kohda M, Nomura M, et al. Sarcoidosis in a patient with autoimmune hemolytic anemia. Nihon Kyobu Shikkan Gakkai Zasshi, 1996 Aug;34(8):931-6. PMID:8965407.
Chernow K, Donegan T, Milman T, Henry D. sarcoidisis, complete heart block, and warm autoimmune hemolytic anemia in a young woman, J Community Support Oncol., 2015 Apr;13(4):159-61. https://doi.org/10.12788/jcso.... PMid:26102609.
Meregalli M, Bosisio R, Delpiano CL, Spinelli M. Monolateral sarcoidosis of parotid gland associated with hemolytic anemia: description of a case diagnosed by cytohistology. Haematologica, 1991 Jul-Aug;76(4):321-3. PMID:1794738.
Thadani U, Aber CP, Taylor JJ. Massive splenomegaly,pancytopenia and haemolytic anaemia in sarcoidosis. Acta Haematol., 1975;53(4):230-40. https://doi.org/10.1159/000208... PMid:808933.
Green S, Partridge E, Idedevbo E, Borg A. Steroid Refractory Autoimmune Haemolytic Anaemia Secondary to Sarcoidosis Successfully Treated with Rituximab and Mycophenolate Mofetil. Case Rep Hematol.,2016;2016:9495761. https://doi.org/10.1155/2016/9... PMid:27563474 PMCid:PMC4985568.
Kondo H, Sakai S, Sakai Y. Autoimmune haemolytic anaemia, Sjögren’s syndrome and idiopathic thrombocytopenic purpura in a patient with sarcoidosis. Acta Haematol., 1993;89(4):209-12. https://doi.org/10.1159/000204... PMid:8213004.
Spitzer T, Crum E, Schacter L, Abboud S. Sarcoidosis, Hodgkin’s disease, and autoimmune hemolytic anemia. Am J Med Sci., 1986 Mar;291(3):190-3. https://doi.org/10.1097/000004... PMid:3953637.
Taillan B, Pedinielli FJ, Routy JP, Blanc AP. Non-Hodgkin malignant lymphoma and autoimmune anemia during the development of sarcoidosis. Rev Med Interne., 1985 Dec;6(5):573-5. https://doi.org/10.1016/S0248-....
Barcellini W. New Insights in the Pathogenesis of Autoimmune Hemolytic Anemia. Transfus Med Hemother, 2015;42:287-93. https://doi.org/10.1159/000439... PMid:26696796 PMCid:PMC4678320.
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