Background: Hearing loss (HL) is one of the most common chronic conditions after hypertension and arthritis. Mounting indices suggest that sensorineural hearing loss (SNHL) may be one of the adverse effects of severe acute respiratory syndrome coronavirus 2.
Objective: This work aimed at studying SNHL in post-COVID-19 patients, alongside with exploring the relationship between severity of the disease and degree of hearing disability.
Materials and methods: This prospective cross-sectional study was conducted at Al-Azhar University Hospitals, Cairo, Egypt. It included 100 post-COVID-19 patients selected according to the study inclusion and exclusion criteria. Pure tone audiometry was done to confirm the presence of HL and to determine its degree.
Results: Hundred patients with recent oncent hearing symptoms after documented COVID-19 infection were included. Males (71%) were more affected than females (29%). The most of our cases had bilateral moderate HL (45%). Tinnitus was the most frequently associated otological symptom (96.96%). The time of HL onset varied from days to weeks (55% had time onset between 11-30 days post-confirmed infection). Higher thresholds were detected in all frequencies of affected ears with more deterioration of hearing as frequencies increase. All degrees of HL were detected; mild, moderate, severe and profound. There was no significant correlation between severity of COVID-19 infection and severity of HL.
Conclusions: SNHL is one of the extrapulmonary complications of COVID-19. COVID-19 patients may develop
hearing affection regardless the severity ofthe infection. Itis recommended to assess hearing functions in patients
after COVID-19 for early detection and proper management.
REFERENCES(25)
1.
Abramovich S, Prasher DK. Electrocochleography and brain-stem potentials in Ramsay Hunt syndrome. Arch Otolaryngol Head Neck Surg. 1986;112(9):925-8. https://doi.org/10.1001/archot... PMid:3741657.
Chern A, Famuyide AO, Moonis G, Lalwani AK. Bilateral sudden sensorineural hearing loss and intralabyrinthine hemorrhage in a patient with COVID-19. Otol Neurotol. 2021;42(1):e10-4. https://doi.org/10.1097/MAO.00... PMid:33301283 PMCid:PMC7737860.
Ozer F, Alkan O. Simultaneous sudden hearing loss and peripheral facial paralysis in a patient with COVID-19. Ear Nose Throat J. 2023;102(11):NP559-64. https://doi.org/10.1177/014556... PMid:34219500.
Sriwijitalai W, Wiwanitkit V. Hearing loss and COVID-19: A note. Am J Otolaryngol. 2020;41(3):102473. https://doi.org/10.1016/j.amjo... PMid:32276732 PMCid: PMC7132500.
Peng F, Tu L, Yang Y, et al. Management and treatment of COVID-19: The Chinese experience. Can J Cardiol. 2020; 36(6):915-30. https://doi.org/10.1016/j.cjca... PMid:32439306 PMCid:PMC7162773.
Zehra A, Gautam HK, Kanaujia SK, et al. Irreversible sensorineural hearing loss in post-COVID-19 patients–An institutional prospective study. Indian J Otolaryngol Head Neck Surg. 2023;75(Suppl 1):424-8. https://doi.org/10.1007/s12070... PMid:36777928 PMCid:PMC9901376.
Helms J, Kremer S, Merdji H, et al. Neurologic features in severe SARS-CoV-2 infection. N Engl J Med. 2020;382(23):2268-70. https://doi.org/10.1056/NEJMc2... PMid:32294339 PMCid:PMC7179967.
Meng X, Wang J, Sun J, Zhu K. COVID-19 and sudden sensorineural hearing loss: A systematic review. Front Neurol. 2022;13:883749. https://doi.org/10.3389/fneur.... PMid:35572936 PMCid:PMC9096262.
Jin JM, Bai P, He W, et al. Gender differences in patients with COVID-19: Focus on severity and mortality. Front Public Health. 2020;8:152. https://doi.org/10.3389/fpubh.... PMid:32411652 PMCid:PMC7201103.
Swain SK, Pani SR. Incidence of hearing loss in COVID-19 patients: A COVID-19 hospital-based study in the Eastern Part of India. Int J Curr Res Rev. 2021;13:103-7. https://doi.org/10.31782/IJCRR....
Shah S, Rocke J, France K, Izzat S. Sudden sensorineural hearing loss in COVID-19: A case series from the Wrightington, Wigan and Leigh Teaching Hospitals, United Kingdom. Med J Malaysia. 2021;76(Suppl 4):55-9. PMid:34558562.
Hegemann SCA, Wenzel A. Diagnosis and treatment of vestibular neuritis/neuronitis or peripheral vestibulopathy (PVP)? Open questions and possible answers. Otol Neurotol. 2017;38(5):626-31. https://doi.org/10.1097/MAO.00... PMid:28346294.
Benghanem S, Mazeraud A, Azabou E, et al. Brainstem dysfunction in critically ill patients. Crit Care. 2020;24(1):5. https://doi.org/10.1186/s13054... PMid:31907011 PMCid:PMC6945639.
Dusan M, Milan S, Nikola D. COVID-19 caused hearing loss. Eur Arch Otorhinolaryngol. 2022;279(5):2363-2. https://doi.org/10.1007/s00405... PMid:34235578 PMCid:PMC8263317.
Uranaka T, Kashio A, Ueha R, et al. Expression of ACE2, TMPRSS2, and furin in mouse ear tissue, and the implications for SARS-CoV-2 infection. Laryngoscope. 2021;131(6):E2013-7. https://doi.org/10.1002/lary.2... PMid:33296096.
Harenberg J, Jonas JB, Trecca EMC. A liaison between sudden sensorineural hearing loss and SARS-CoV-2 infection. Thromb Haemost. 2020;120(9):1237-9. https://doi.org/10.1055/s-0040... PMid:32725610.
Shi X, Liu X, Sun Y. The pathogenesis of cytomegalovirus and other viruses associated with hearing loss: Recent updates. Viruses. 2023;15(6):1385. https://doi.org/10.3390/v15061... PMid:37376684 PMCid:PMC10305308.
Yamada S, Kita J, Shinmura D, et al. Update on findings about sudden sensorineural hearing loss and insight into its pathogenesis. J Clin Med. 2022;11(21):6387. https://doi.org/10.3390/jcm112... PMid:36362614 PMCid:PMC9653771.
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.