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ORIGINAL ARTICLE
Temporal trends and demographic variations in hospitalizations with angiodysplasia of the intestine: A U.S. population based study
1
Guthrie Robert Packer Hospital, Sayre, PA, USA
2
Henry Ford Hospital, Detroit, MI, USA
3
New York Medical College at Westchester Medical Center, Valhalla, NY, USA
4
University of Toledo Medical Center, Toledo, OH, USA
5
University of Tennessee Health Science Center, Memphis, TN, USA
6
St. Barnabas Medical Center, Livingston, NJ, USA
Online publication date: 2018-09-16
Publication date: 2018-09-16
Corresponding author
Shantanu Devanand Solanki
Guthrie Robert Packer Hospital, Sayre, PA, 100 Woods Road, 10595 Valhalla, United States
Guthrie Robert Packer Hospital, Sayre, PA, 100 Woods Road, 10595 Valhalla, United States
Electron J Gen Med 2018;15(5):em80
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Angiodysplasia is the most common vascular lesion of the gastrointestinal (GI) tract. However, limited epidemiological data exists on hospitalizations related to angiodysplasia of the intestine (ADOI) in the United States (U.S.). The aim of this study is to analyze inpatient trends and outcomes in hospitalizations with ADOI.
Methods:
We analyzed the National Inpatient Sample (NIS) database for all subjects with discharge diagnosis of angiodysplasia of the intestine with or without hemorrhage (ICD-9 code 569.85 and 569.84 respectively) as principal and/or secondary diagnosis during the period from 2001 to 2011.
Results:
In 2001, there were 39,244 admissions with discharge diagnosis of ADOI as compared to 41,214 in 2011 (p <0.0001). Women (58.0%) were more commonly affected than men (42.0%) (p < 0.0001). Overall in-hospital mortality rate was 2.2% for patients with ADOI with hemorrhage and 1.6% for patients with ADOI without hemorrhage (p <0.0001). Mean cost of hospitalization increased from ,701 in 2001 to ,478 in 2011 (16.6% increase, p < 0.0001).
Conclusion:
The total number of hospitalizations with ADOI increased significantly with women having significantly higher hospitalization rates. Mortality rate was higher in hospitalizations with ADOI with hemorrhage than those without hemorrhage. There was a notable increase in the average cost of hospitalization.
Angiodysplasia is the most common vascular lesion of the gastrointestinal (GI) tract. However, limited epidemiological data exists on hospitalizations related to angiodysplasia of the intestine (ADOI) in the United States (U.S.). The aim of this study is to analyze inpatient trends and outcomes in hospitalizations with ADOI.
Methods:
We analyzed the National Inpatient Sample (NIS) database for all subjects with discharge diagnosis of angiodysplasia of the intestine with or without hemorrhage (ICD-9 code 569.85 and 569.84 respectively) as principal and/or secondary diagnosis during the period from 2001 to 2011.
Results:
In 2001, there were 39,244 admissions with discharge diagnosis of ADOI as compared to 41,214 in 2011 (p <0.0001). Women (58.0%) were more commonly affected than men (42.0%) (p < 0.0001). Overall in-hospital mortality rate was 2.2% for patients with ADOI with hemorrhage and 1.6% for patients with ADOI without hemorrhage (p <0.0001). Mean cost of hospitalization increased from ,701 in 2001 to ,478 in 2011 (16.6% increase, p < 0.0001).
Conclusion:
The total number of hospitalizations with ADOI increased significantly with women having significantly higher hospitalization rates. Mortality rate was higher in hospitalizations with ADOI with hemorrhage than those without hemorrhage. There was a notable increase in the average cost of hospitalization.
REFERENCES (32)
1.
Regula J, Wronska E, Pachlewski J. Vascular lesions of the gastrointestinal tract. Best Pract Res Clin Gastroenterol 2008;22(2):313-28. https://doi.org/10.1016/j.bpg..... PMid:18346686.
2.
Sami SS, Al-Araji SA, Ragunath K. Review article: gastrointestinal angiodysplasia - pathogenesis, diagnosis and management. Aliment Pharmacol Ther. 2014;39(1):15-34. https://doi.org/10.1111/apt.12.... PMid:24138285.
3.
Foutch PG. Angiodysplasia of the gastrointestinal tract. Am J Gastroenterol 1993, 88(6):807-18. PMid:8389094.
4.
Overview of the National (Nationwide) Inpatient Sample (NIS). Retrieved on 17 January 2018 from https://www.hcup-us.ahrq.gov/n....
7.
Badheka AO, Chothani A, Mehta K, et al. Utilization and adverse outcomes of percutaneous left atrial appendage closure for stroke prevention in atrial fibrillation in the United States: influence of hospital volume. Circ Arrhythm Electrophysiol. 2015;8(1):42-8. https://doi.org/10.1161/CIRCEP... PMid:25480543.
8.
Patel NJ, Deshmukh A, Pant S, et al. Contemporary trends of hospitalization for atrial fibrillation in the United States, 2000 through 2010: implications for healthcare planning. Circulation 2014;129(23):2371-9. https://doi.org/10.1161/CIRCUL... PMid:24842943.
9.
Singh V, Rodriguez AP, Thakkar B, et al. Hospital Admissions for Chest Pain Associated with Cocaine Use in the United States. Am J Med. 2017;130(6):688-98. https://doi.org/10.1016/j.amjm... PMid:28063854.
10.
Population and Housing Unit Estimates. Retrieved on 18 January 2018 from https://www.census.gov/program....
13.
Armitage P: Tests for Linear Trends in Proportions and Frequencies. Biometrics 1955;11(3):375-386. https://doi.org/10.2307/300177....
14.
Nahm FS: Nonparametric statistical tests for the continuous data: the basic concept and the practical use. Korean J Anesthesiol 2016;69(1):8-14. https://doi.org/10.4097/kjae.2... PMid:26885295 PMCid:PMC4754273.
15.
Boley SJ, Sammartano R, Adams A, et al. On the nature and etiology of vascular ectasias of the colon. Degenerative lesions of aging. Gastroenterology 1977;72(4 Pt 1):650-60. PMid:300063.
16.
Clouse RE, Costigan DJ, Mills BA, et al. Angiodysplasia as a cause of upper gastrointestinal bleeding. Arch Intern Med. 1985;145(3):458-61. https://doi.org/10.1001/archin... PMid:3872107.
17.
Richter JM, Hedberg SE, Athanasoulis CA, et al. Angiodysplasia. Clinical presentation and colonoscopic diagnosis. Dig Dis Sci. 1984;29(6):481-5. https://doi.org/10.1007/BF0129... PMid:6609803.
18.
Cappell MS. Spatial clustering of simultaneous nonhereditary gastrointestinal angiodysplasia. Small but significant correlation between nonhereditary colonic and upper gastrointestinal angiodysplasia. Dig Dis Sci. 1992;37(7):1072-7. https://doi.org/10.1007/BF0130... PMid:1618055.
19.
Jackson CS, Strong R. Gastrointestinal Angiodysplasia: Diagnosis and Management. Gastrointest Endosc Clin N Am. 2017;27(1):51-62. https://doi.org/10.1016/j.giec... PMid:27908518.
20.
Godeschalk MF, Mensink PB, van Buuren HR, et al. Primary balloon-assisted enteroscopy in patients with obscure gastrointestinal bleeding: findings and outcome of therapy. J Clin Gastroenterol. 2010;44(9):e195-200. https://doi.org/10.1097/MCG.0b... PMid:20505527.
21.
Prachayakul V, Deesomsak M, Aswakul P, et al. The utility of single-balloon enteroscopy for the diagnosis and management of small bowel disorders according to their clinical manifestations: a retrospective review. BMC Gastroenterol. 2013;13:103. https://doi.org/10.1186/1471-2... PMid:23800178 PMCid:PMC3716953.
22.
Pandey V, Ingle M, Pandav N, et al. The role of capsule endoscopy in etiological diagnosis and management of obscure gastrointestinal bleeding. Intest Res. 2016;14(1):69-74. https://doi.org/10.5217/ir.201... PMid:26884737 PMCid:PMC4754525.
23.
Shah AR, Jala V, Arshad H, et al. Evaluation and management of lower gastrointestinal bleeding. Dis Mon 2018. https://doi.org/10.1016/j.disa... PMid:29525374.
24.
Hernandez I, Saba S, Zhang Y. Geographic Variation in the Use of Oral Anticoagulation Therapy in Stroke Prevention in Atrial Fibrillation. Stroke 2017;48(8):2289-91. https://doi.org/10.1161/STROKE... PMid:28655815.
25.
Urgesi R, Cianci R, Pagliari D, et al. Is capsule endoscopy appropriate for elderly patients? The influence of ageing on findings and diagnostic yield: An Italian retrospective study. Dig Liver Dis. 2015;47(12):1086-8. https://doi.org/10.1016/j.dld.... PMid:26514739.
26.
Sidhu R, Sanders DS. Double-balloon enteroscopy in the elderly with obscure gastrointestinal bleeding: safety and feasibility. Eur J Gastroenterol Hepatol. 2013;25(10):1230-4. https://doi.org/10.1097/.
28.
Li L, Chen C, Li Y, et al. The role of capsule endoscopy in the diagnosis and treatment of obscure gastrointestinal bleeding in older individuals. Eur J Gastroenterol Hepatol. 2016;28(12):1425-30. https://doi.org/10.1097/MEG.00... PMid:27603298.
29.
Olmos JA, Marcolongo M, Pogorelsky V, et al. Argon plasma coagulation for prevention of recurrent bleeding from GI angiodysplasias. Gastroint. Endosc. 2004;60(6):881-6. https://doi.org/10.1016/S0016-....
30.
Schneeweiss S, Avorn J. A review of uses of health care utilization databases for epidemiologic research on therapeutics. J Clin Epidemiol. 2005;58(4):323-37. https://doi.org/10.1016/j.jcli... PMid:15862718.
31.
Liao Z, Gao R, Xu C, et al. Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review. Gastrointest Endosc. 2010;71(2):280-6. https://doi.org/10.1016/.
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