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REVIEW ARTICLE
The interaction of glutathione and thymoquinone and their antioxidant properties
1
Professor of Medical Biochemistry, Private Esencan Hospital Esenyurt, Istanbul, Turkey
2
Associate Professor of Medical Biochemistry, 225 Fluor Daniel Dr., Houston, TX 77479, USA
3
Professor of Medical Biochemistry, 225 Fluor Daniel Dr., Houston, TX 77479, USA
Online publication date: 2018-04-15
Publication date: 2018-04-15
Electron J Gen Med 2018;15(4):em59
KEYWORDS
TOPICS
ABSTRACT
Protein S-glutathionylation has been regarded as one of the main mechanisms that control cell signaling and metabolic regulation. Several diseases including cardiovascular diseases, diabetes, neurodegenerative diseases and many types of cancer have been certainly found to be related with S-glutathionylation. It can be regarded as a promising area for therapeutic and diagnostic approaches in many diseases. In this mini review, we aimed to summarize and compare the interaction of glutathione (GSH) and thymoquinone (TQ), and elucidate the possible synergistic mechanisms of antioxidant and other beneficial effects.
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